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Cialix ejection fraction but struggle regeneration dp/dt and other measures of load independent contract ility now on the bottom panel is an e F and G we started to again continue to chase down this SD f1 pathway a bit further and found that there was a difference that we saw that with primary unloading there was a higher concentration of circulating as well as myocardial SD F 1 alpha in the hearts and in circulation and that the plasma SD F 1 alpha level correlated inversely with scar size the more SD f1 around the smaller the scar size now when we looked at the non infarct or remote regions 28 days later we also wanted to see whether we were affecting fetal gene expression and other canonical pathways of maladaptive remodelling and what we found was that in fact things such as BMP expression a marker of congestion or heart failure both at the microbial level in in the circulation were reduced 28 days later we also found that circa calcineurin collagen as a measure of fibrotic are